Research ArticleCancer
Immunological mechanisms of the antitumor effects of supplemental oxygenation
- Stephen M. Hatfield1,
- Jorgen Kjaergaard1,
- Dmitriy Lukashev1,
- Taylor H. Schreiber2,*,
- Bryan Belikoff1,
- Robert Abbott1,
- Shalini Sethumadhavan1,
- Phaethon Philbrook1,
- Kami Ko1,
- Ryan Cannici1,
- Molly Thayer1,
- Scott Rodig3,
- Jeffrey L. Kutok3,†,
- Edwin K. Jackson4,
- Barry Karger5,
- Eckhard R. Podack2,
- Akio Ohta1 and
- Michail V. Sitkovsky1,6,‡
- 1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
- 2Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
- 3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, 20 Shattuck Street, Boston, MA 02115, USA.
- 4Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
- 5Barnett Institute of Chemical and Biological Analysis, Northeastern University, Boston, MA 02115, USA.
- 6Cancer Vaccine Center, Dana-Farber Cancer Institute, Harvard Institutes of Medicine, 44 Binney Street, Boston, MA 02115, USA.
- ↵‡Corresponding author. E-mail: m.sitkovsky{at}neu.edu
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Science Translational Medicine 04 Mar 2015:
Vol. 7, Issue 277, pp. 277ra30
DOI: 10.1126/scitranslmed.aaa1260
Vol. 7, Issue 277, pp. 277ra30
DOI: 10.1126/scitranslmed.aaa1260
Stephen M. Hatfield
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Jorgen Kjaergaard
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Dmitriy Lukashev
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Taylor H. Schreiber
2Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Bryan Belikoff
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Robert Abbott
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Shalini Sethumadhavan
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Phaethon Philbrook
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Kami Ko
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Ryan Cannici
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Molly Thayer
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Scott Rodig
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, 20 Shattuck Street, Boston, MA 02115, USA.
Jeffrey L. Kutok
3Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, 20 Shattuck Street, Boston, MA 02115, USA.
Edwin K. Jackson
4Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
Barry Karger
5Barnett Institute of Chemical and Biological Analysis, Northeastern University, Boston, MA 02115, USA.
Eckhard R. Podack
2Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Akio Ohta
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Michail V. Sitkovsky
1New England Inflammation and Tissue Protection Institute, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
6Cancer Vaccine Center, Dana-Farber Cancer Institute, Harvard Institutes of Medicine, 44 Binney Street, Boston, MA 02115, USA.
