Intraoperative brain cancer detection with Raman spectroscopy in humans

Michael Jermyn; Kelvin Mok; Jeanne Mercier; Joannie Desroches; Julien Pichette; Karl Saint-Arnaud; Liane Bernstein; Marie-Christine Guiot; Kevin Petrecca; Frederic Leblond

doi:10.1126/scitranslmed.aaa2384

Research ArticleCancer Imaging

Intraoperative brain cancer detection with Raman spectroscopy in humans

Michael Jermyn¹,²,*,
Kelvin Mok³,*,
Jeanne Mercier²,
Joannie Desroches⁴,
Julien Pichette²,
Karl Saint-Arnaud²,
Liane Bernstein²,
Marie-Christine Guiot¹,⁵,
Kevin Petrecca¹,†,‡ and
Frederic Leblond²,†,‡

¹Brain Tumour Research Centre, Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.
²Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.
³Neuronavigation Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec H3A 2B4, Canada.
⁴Medical Physics Unit, McGill University, 1650 Cedar Avenue, Montreal, Quebec H3G 1A4, Canada.
⁵Division of Neuropathology, Department of Pathology, McGill University, Montreal, Quebec H3A 2B4, Canada.

↵‡Corresponding author. E-mail: kevin.petrecca{at}mcgill.ca (K.P.); leblondfrederic{at}gmail.com (F.L.)

↵* These authors contributed equally to this work.
↵† These authors contributed equally to this work.

See allHide authors and affiliations

Science Translational Medicine 11 Feb 2015:
Vol. 7, Issue 274, pp. 274ra19
DOI: 10.1126/scitranslmed.aaa2384

Michael Jermyn

Brain Tumour Research Centre, Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kelvin Mok

Neuronavigation Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec H3A 2B4, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jeanne Mercier

Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Joannie Desroches

Medical Physics Unit, McGill University, 1650 Cedar Avenue, Montreal, Quebec H3G 1A4, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Julien Pichette

Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Karl Saint-Arnaud

Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Liane Bernstein

Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Marie-Christine Guiot

Brain Tumour Research Centre, Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.Division of Neuropathology, Department of Pathology, McGill University, Montreal, Quebec H3A 2B4, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kevin Petrecca

Brain Tumour Research Centre, Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: kevin.petrecca@mcgill.ca leblondfrederic@gmail.com

Frederic Leblond

Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: kevin.petrecca@mcgill.ca leblondfrederic@gmail.com

Article
Figures & Data
Info & Metrics
eLetters
PDF

eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all. Please read our Terms of Service before submitting your own eLetter.

Submit a Response to This Article

Compose eLetter

Title

Contents

More information about text formats

Plain text

Plain text
No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First name and middle name First or given name, e.g. 'Peter'. Last Name Your last, or family, name, e.g. 'MacMoody'. Email Your email address, e.g. higgs-boson@gmail.com Role / Occupation Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests?

Yes

Please describe the competing interests

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

What code is in the image? Enter the characters shown in the image.

Vertical Tabs

No eLetters have been published for this article.

View Full Text

Intraoperative brain cancer detection with Raman spectroscopy in humans

Plain text

Vertical Tabs

Science Translational Medicine

Article Tools