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Local iontophoretic administration of cytotoxic therapies to solid tumors

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Science Translational Medicine  04 Feb 2015:
Vol. 7, Issue 273, pp. 273ra14
DOI: 10.1126/scitranslmed.3009951

Article Information

vol. 7 no. 273 273ra14

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 2, 2014
  • Accepted for publication December 18, 2014
  • .

Author Information

  1. James D. Byrne1,2,*,
  2. Mohammad N. R. Jajja3,*,
  3. Adrian T. O’Neill3,
  4. Lissett R. Bickford3,
  5. Amanda W. Keeler4,
  6. Nabeel Hyder5,
  7. Kyle Wagner5,
  8. Allison Deal6,
  9. Ryan E. Little2,
  10. Richard A. Moffitt3,
  11. Colleen Stack3,7,8,
  12. Meredith Nelson3,
  13. Christopher R. Brooks9,
  14. William Lee10,
  15. J. Chris Luft1,3,
  16. Mary E. Napier3,
  17. David Darr3,
  18. Carey K. Anders3,11,
  19. Richard Stack3,8,12,
  20. Joel E. Tepper3,5,
  21. Andrew Z. Wang3,5,
  22. William C. Zamboni3,4,
  23. Jen Jen Yeh3,13,14, and
  24. Joseph M. DeSimone1,3,10,14,15,
  1. 1Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  2. 2School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  3. 3Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  4. 4Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  5. 5Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  6. 6Lineberger Comprehensive Cancer Center Biostatistics and Clinical Data Management Core, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  7. 7School of Medicine, Duke University, Durham, NC 27708, USA.
  8. 8Synecor LLC, Chapel Hill, NC 27517, USA.
  9. 9Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  10. 10Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  11. 11Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  12. 12Division of Cardiology, Department of Medicine, Duke University, Durham, NC 27708, USA.
  13. 13Division of Surgical Oncology, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  14. 14Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  15. 15Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC 27695, USA.
  1. Corresponding author. E-mail: jen_jen_yeh{at}med.unc.edu (J.J.Y); desimone{at}unc.edu (J.M.D.)
    • * These authors contributed equally to this work.

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