Research ArticleCARDIAC SIDE EFFECTS

Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase

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Science Translational Medicine  10 Dec 2014:
Vol. 6, Issue 266, pp. 266ra170
DOI: 10.1126/scitranslmed.3010189

Article Information

vol. 6 no. 266 266ra170

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 28, 2014
  • Accepted for publication October 3, 2014

Author Information

  1. Yan Liu1,2,*,
  2. Aarti Asnani1,2,*,
  3. Lin Zou3,
  4. Victoria L. Bentley4,
  5. Min Yu5,
  6. You Wang1,2,
  7. Graham Dellaire4,6,
  8. Kumar S. Sarkar1,2,
  9. Matthew Dai1,
  10. Howard H. Chen1,7,
  11. David E. Sosnovik1,7,
  12. Jordan T. Shin1,
  13. Daniel A. Haber5,8,
  14. Jason N. Berman9,10,
  15. Wei Chao3 and
  16. Randall T. Peterson1,2,
  1. 1Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  2. 2Broad Institute, Cambridge, MA 02142, USA.
  3. 3Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  4. 4Department of Pathology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
  5. 5Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA.
  6. 6Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
  7. 7Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  8. 8Howard Hughes Medical Institute.
  9. 9Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia B3H 4R2, Canada.
  10. 10Department of Pediatrics, Izaak Walton Killam Health Centre, Halifax, Nova Scotia B3K 6R8, Canada.
  1. Corresponding author. E-mail: rtpeterson{at}mgh.harvard.edu
    • * These authors contributed equally to this work.

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