10 December 2014
Vol 6, Issue 266

About The Cover

Cover image expansion

ONLINE COVER To See Again. Shown is a representation of the human visual pathway, including the optic chiasm and tracts (purple) and radiations (blue, yellow, and pink) revealed by magnetic resonance imaging. The subject had a large pituitary tumor (red) that caused compression and demyelination of the optic chiasm resulting in vision loss. Surgical removal of the tumor resulted in rapid remyelination and vision recovery in this patient and others (Paul et al.). Elucidation of the principles that govern such rapid remyelination should have therapeutic implications for other kinds of central nervous system injury [CREDIT: D. A. PAUL/UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE]