Research ArticleHerpes Simplex Virus

Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes

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Science Translational Medicine  03 Dec 2014:
Vol. 6, Issue 265, pp. 265ra169
DOI: 10.1126/scitranslmed.3010643

Article Information

vol. 6 no. 265 265ra169

PubMed: 
Print ISSN: 
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History: 
  • Received for publication September 10, 2014
  • Accepted for publication November 5, 2014
  • .

Author Information

  1. James M. Hill1,*,
  2. Debra C. Quenelle2,
  3. Rhonda D. Cardin3,
  4. Jodi L. Vogel4,
  5. Christian Clement1,,
  6. Fernando J. Bravo3,
  7. Timothy P. Foster1,
  8. Marta Bosch-Marce5,
  9. Priya Raja6,
  10. Jennifer S. Lee6,7,
  11. David I. Bernstein3,
  12. Philip R. Krause5,
  13. David M. Knipe6,7 and
  14. Thomas M. Kristie4,
  1. 1Department of Ophthalmology and Department of Microbiology, Immunology, and Parasitology, LSU Eye Center, Louisiana State University Health Science Center School of Medicine, New Orleans, LA 70112, USA.
  2. 2Department of Pediatric Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  3. 3Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA.
  4. 4National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  5. 5Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20852, USA.
  6. 6Department of Microbiology and Immunology, Harvard Medical School, Boston, MA 02115, USA.
  7. 7Harvard Program in Virology, Harvard Medical School, Boston, MA 02115, USA.
  1. Corresponding author. E-mail: tkristie{at}niaid.nih.gov
  • * It is with sadness and respect that we mark the passing of our colleague J.M.H.

  • Present address: Department of Natural Sciences, Southern University at New Orleans, New Orleans, LA 70126, USA.

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