Contents
Vol 6, Issue 265
Contents
Research Articles
- PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis
PET/CT imaging in humans with TB correlates with drug response and final treatment outcomes.
- PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis
PET/CT imaging in macaques and humans with TB shows a beneficial therapeutic response to linezolid and a new oxazolidinone antibiotic, AZD5847.
- Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders
Molecular diagnosis of pediatric neurodevelopmental disorders by genomic sequencing is frequently informative and cost-effective and can affect clinical care.
- Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes
Epigenetic suppression of herpes simplex virus demonstrates an approach to control persistent viruses.
State of the Art Review
- Wound repair and regeneration: Mechanisms, signaling, and translation
The combination of an advanced scientific understanding of tissue repair and regeneration and the identification of knowledge gaps and the limitations of past clinical trials will provide a strong basis to advance viable clinical approaches for treating patients with wound-healing pathologies.
Editors' Choice
- Watch Your Leftovers: Remnant Cholesterol Brings Oversized Risk to Cardiovascular Health
A large-scale analysis of a Copenhagen cohort reveals mediators of cardiovascular risk for obese individuals.
- Filled with Evil: Molecular Signatures of Tumor-Associated Immune Cells
Molecular profiling unveils how monocytes and macrophages in human renal cancers contribute to tumor progression.
- Morphing Cell Identity to Treat Diabetes
An optimized protocol enables in vivo conversion of pancreatic acinar cells to functional pancreatic beta cells with implications for treating diabetes.
