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Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin

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Science Translational Medicine  05 Nov 2014:
Vol. 6, Issue 261, pp. 261ra152
DOI: 10.1126/scitranslmed.3009318

Article Information

vol. 6 no. 261 261ra152

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 15, 2014
  • Accepted for publication September 18, 2014
  • .

Author Information

  1. Ashley M. Laughney1,
  2. Eunha Kim1,
  3. Melissa M. Sprachman1,
  4. Miles A. Miller1,
  5. Rainer H. Kohler1,
  6. Katy S. Yang1,
  7. James D. Orth2,*,
  8. Timothy J. Mitchison2 and
  9. Ralph Weissleder1,2,
  1. 1Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge Street, CPZN 5206, Boston, MA 02114, USA.
  2. 2Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
  1. Corresponding author. E-mail: rweissleder{at}mgh.harvard.edu
    • * Present address: Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, 347 UCB, Boulder, CO 80309, USA.

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