Research ArticleImmunotherapy

Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity

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Science Translational Medicine  05 Nov 2014:
Vol. 6, Issue 261, pp. 261ra151
DOI: 10.1126/scitranslmed.3010162

Article Information

vol. 6 no. 261 261ra151

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 24, 2014
  • Accepted for publication October 9, 2014
  • .

Author Information

  1. Prasad S. Adusumilli1,2,*,
  2. Leonid Cherkassky1,2,,
  3. Jonathan Villena-Vargas1,2,,
  4. Christos Colovos1,2,
  5. Elliot Servais1,2,
  6. Jason Plotkin1,
  7. David R. Jones2 and
  8. Michel Sadelain1,3,*
  1. 1Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  2. 2Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  3. 3Immunology Program, Sloan Kettering Institute, New York, NY 10065, USA.
  1. *Corresponding author. E-mail: adusumip{at}mskcc.org (P.S.A.); sadelaim{at}mskcc.org (M.S.)
    • These authors contributed equally to this work and should be considered as second authors.

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