Endoscopic molecular imaging of human bladder cancer using a CD47 antibody

Ying Pan; Jens-Peter Volkmer; Kathleen E. Mach; Robert V. Rouse; Jen-Jane Liu; Debashis Sahoo; Timothy C. Chang; Thomas J. Metzner; Lei Kang; Matt van de Rijn; Eila C. Skinner; Sanjiv S. Gambhir; Irving L. Weissman; Joseph C. Liao

doi:10.1126/scitranslmed.3009457

Research ArticleCancer Imaging

Endoscopic molecular imaging of human bladder cancer using a CD47 antibody

Ying Pan¹,²,
Jens-Peter Volkmer³,
Kathleen E. Mach¹,²,
Robert V. Rouse²,⁴,
Jen-Jane Liu¹,
Debashis Sahoo³,
Timothy C. Chang¹,
Thomas J. Metzner¹,
Lei Kang¹,²,
Matt van de Rijn⁴,
Eila C. Skinner¹,
Sanjiv S. Gambhir⁵,
Irving L. Weissman³,⁴,* and
Joseph C. Liao¹,²,*,†

¹Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.
²Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.
³Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA.
⁴Department of Pathology, Stanford University, Stanford, CA 94305, USA.
⁵Molecular Imaging Program at Stanford and Departments of Radiology and Bioengineering, Stanford University, Stanford, CA 94305, USA.

↵†Corresponding author. E-mail: jliao{at}stanford.edu

↵* These authors contributed equally to this work.

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Science Translational Medicine 29 Oct 2014:
Vol. 6, Issue 260, pp. 260ra148
DOI: 10.1126/scitranslmed.3009457

Ying Pan

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.

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Jens-Peter Volkmer

3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA.

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Kathleen E. Mach

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.

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Robert V. Rouse

2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.

4Department of Pathology, Stanford University, Stanford, CA 94305, USA.

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Jen-Jane Liu

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

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Debashis Sahoo

3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA.

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Timothy C. Chang

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

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Thomas J. Metzner

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

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Lei Kang

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.

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Matt van de Rijn

4Department of Pathology, Stanford University, Stanford, CA 94305, USA.

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Eila C. Skinner

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

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Sanjiv S. Gambhir

5Molecular Imaging Program at Stanford and Departments of Radiology and Bioengineering, Stanford University, Stanford, CA 94305, USA.

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Irving L. Weissman

3Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA.

4Department of Pathology, Stanford University, Stanford, CA 94305, USA.

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Joseph C. Liao

1Department of Urology and Bio-X Program, Stanford University, Stanford, CA 94305, USA.

2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.

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For correspondence: jliao@stanford.edu

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Endoscopic molecular imaging of human bladder cancer using a CD47 antibody

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