A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation

Marianne Delville; Tara K. Sigdel; Changli Wei; Jing Li; Szu-Chuan Hsieh; Alessia Fornoni; George W. Burke; Patrick Bruneval; Maarten Naesens; Annette Jackson; Nada Alachkar; Guillaume Canaud; Christophe Legendre; Dany Anglicheau; Jochen Reiser; Minnie M. Sarwal

doi:10.1126/scitranslmed.3008538

Research ArticleKidney Disease

A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation

Marianne Delville¹,*,
Tara K. Sigdel²,*,
Changli Wei³,*,
Jing Li³,
Szu-Chuan Hsieh²,
Alessia Fornoni⁴,
George W. Burke⁵,
Patrick Bruneval⁶,
Maarten Naesens⁷,
Annette Jackson⁸,
Nada Alachkar⁸,
Guillaume Canaud¹,
Christophe Legendre¹,
Dany Anglicheau¹,†,
Jochen Reiser³,†‡ and
Minnie M. Sarwal²,†‡

¹Department of Kidney Transplantation, Necker Hospital, Assistance Publique–Hôpitaux de Paris, Université Paris Descartes Sorbonne Paris Cité, INSERM U1171, Réseau Thématique de Recherche et de Soins Centaure, Labex Transplantex, 75015 Paris, France.
²Division of Transplant Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
³Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA.
⁴Peggy and Harold Katz Family Drug Discovery Center, Division of Nephrology and Hypertension, University of Miami School of Medicine, Miami, FL 33146, USA.
⁵Division of Transplant Surgery, University of Miami School of Medicine, Miami, FL 33146, USA.
⁶Department of Pathology, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France.
⁷Nephrology and Renal Transplantation, University Hospitals Leuven, 3000 Leuven, Belgium.
⁸Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

↵‡Corresponding author. E-mail: minnie.sarwal{at}ucsf.edu (M.M.S.); jochen_reiser{at}rush.edu (J.R.)

↵* Joint first authors.
↵† Joint senior authors.

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Science Translational Medicine 01 Oct 2014:
Vol. 6, Issue 256, pp. 256ra136
DOI: 10.1126/scitranslmed.3008538

Marianne Delville

1Department of Kidney Transplantation, Necker Hospital, Assistance Publique–Hôpitaux de Paris, Université Paris Descartes Sorbonne Paris Cité, INSERM U1171, Réseau Thématique de Recherche et de Soins Centaure, Labex Transplantex, 75015 Paris, France.

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Tara K. Sigdel

2Division of Transplant Surgery, University of California San Francisco, San Francisco, CA 94143, USA.

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Changli Wei

3Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA.

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Jing Li

3Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA.

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Szu-Chuan Hsieh

2Division of Transplant Surgery, University of California San Francisco, San Francisco, CA 94143, USA.

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Alessia Fornoni

4Peggy and Harold Katz Family Drug Discovery Center, Division of Nephrology and Hypertension, University of Miami School of Medicine, Miami, FL 33146, USA.

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George W. Burke

5Division of Transplant Surgery, University of Miami School of Medicine, Miami, FL 33146, USA.

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Patrick Bruneval

6Department of Pathology, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France.

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Maarten Naesens

7Nephrology and Renal Transplantation, University Hospitals Leuven, 3000 Leuven, Belgium.

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Annette Jackson

8Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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Nada Alachkar

8Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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Guillaume Canaud

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Christophe Legendre

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Dany Anglicheau

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Jochen Reiser

3Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA.

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For correspondence: minnie.sarwal@ucsf.edu jochen_reiser@rush.edu

Minnie M. Sarwal

2Division of Transplant Surgery, University of California San Francisco, San Francisco, CA 94143, USA.

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For correspondence: minnie.sarwal@ucsf.edu jochen_reiser@rush.edu

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A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation

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