Research ArticleCancer

Prostate cancer cell–stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases

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Science Translational Medicine  03 Sep 2014:
Vol. 6, Issue 252, pp. 252ra122
DOI: 10.1126/scitranslmed.3009332

Article Information

vol. 6 no. 252 252ra122

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 17, 2014
  • Accepted for publication July 31, 2014

Author Information

  1. Xinhai Wan1,*,
  2. Paul G. Corn1,*,
  3. Jun Yang1,
  4. Nallasivam Palanisamy2,
  5. Michael W. Starbuck1,3,
  6. Eleni Efstathiou1,4,
  7. Elsa M. Li Ning Tapia1,
  8. Amado J. Zurita1,
  9. Ana Aparicio1,
  10. Murali K. Ravoori5,
  11. Elba S. Vazquez6,
  12. Dan R. Robinson2,
  13. Yi-Mi Wu2,
  14. Xuhong Cao2,
  15. Matthew K. Iyer2,
  16. Wallace McKeehan7,
  17. Vikas Kundra5,8,
  18. Fen Wang7,
  19. Patricia Troncoso9,
  20. Arul M. Chinnaiyan2,
  21. Christopher J. Logothetis1 and
  22. Nora M. Navone1,
  1. 1Department of Genitourinary Medical Oncology and the David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  2. 2Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
  3. 3The Rolanette and Berdon Lawrence Bone Disease Program of Texas, Houston, TX 77030, USA.
  4. 4University of Athens Greece School of Medicine, Athens 11528, Greece.
  5. 5Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  6. 6Department of Biological Chemistry, University of Buenos Aires–National Research Council of Argentina (CONICET-IQUIBICEN), Ciudad Autonoma de Buenos Aires C1428EGA, Argentina.
  7. 7Center for Cancer and Stem Cell Biology, IBT-Texas A&M Health Science Center, Houston, TX 77030, USA.
  8. 8Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  9. 9Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  1. Corresponding author. E-mail: nnavone{at}mdanderson.org
    • * These authors contributed equally to this work.

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