Research ArticleCancer

Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses

See allHide authors and affiliations

Science Translational Medicine  13 Aug 2014:
Vol. 6, Issue 249, pp. 249ra111
DOI: 10.1126/scitranslmed.3008982

Article Information

vol. 6 no. 249 249ra111

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 10, 2014
  • Accepted for publication July 25, 2014
  • .

Author Information

  1. Nicholas J. Roberts1,*,
  2. Linping Zhang2,*,
  3. Filip Janku3,*,
  4. Amanda Collins2,*,
  5. Ren-Yuan Bai4,*,
  6. Verena Staedtke4,5,*,
  7. Anthony W. Rusk6,
  8. David Tung2,
  9. Maria Miller2,
  10. Jeffrey Roix2,
  11. Kristen V. Khanna6,
  12. Ravi Murthy7,
  13. Robert S. Benjamin8,
  14. Thorunn Helgason3,
  15. Ariel D. Szvalb9,
  16. Justin E. Bird10,
  17. Sinchita Roy-Chowdhuri11,
  18. Halle H. Zhang2,
  19. Yuan Qiao1,
  20. Baktiar Karim12,
  21. Jennifer McDaniel13,
  22. Amanda Elpiner14,
  23. Alexandra Sahora15,
  24. Joshua Lachowicz16,
  25. Brenda Phillips17,
  26. Avenelle Turner18,
  27. Mary K. Klein19,
  28. Gerald Post13,
  29. Luis A. Diaz Jr1,20,
  30. Gregory J. Riggins4,
  31. Nickolas Papadopoulos1,
  32. Kenneth W. Kinzler1,
  33. Bert Vogelstein1,
  34. Chetan Bettegowda1,4,
  35. David L. Huso12,
  36. Mary Varterasian2,
  37. Saurabh Saha2,*, and
  38. Shibin Zhou1,*
  1. 1The Ludwig Center for Cancer Genetics and Therapeutics and The Howard Hughes Medical Institute at The Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.
  2. 2BioMed Valley Discoveries Inc., 4520 Main Street, Kansas City, MO 64111, USA.
  3. 3Department of Investigational Cancer Therapeutics (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  4. 4Department of Neurosurgery, The Johns Hopkins Medical Institutes, Baltimore, MD 21231, USA.
  5. 5Department of Neurology, The Johns Hopkins Medical Institutes, Baltimore, MD 21231, USA.
  6. 6Animal Clinical Investigation LLC, 4926 Wisconsin Avenue, NW Washington, DC 20016, USA.
  7. 7Department of Interventional Radiology, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  8. 8Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  9. 9Department of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  10. 10Department of Orthopedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  11. 11Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
  12. 12Department of Molecular and Comparative Pathobiology, The Johns Hopkins University, Baltimore, MD 21205, USA.
  13. 13The Veterinary Cancer Center, 129 Glover Avenue, Norwalk, CT 06850, USA.
  14. 14VCA Great Lakes Veterinary Specialists, 5035 Richmond Road, Bedford Heights, OH 44146, USA.
  15. 15The Oncology Service, Friendship Hospital for Animals, 4105 Brandywine Street, NW, Washington, DC 20016, USA.
  16. 16BluePearl Veterinary Partners, 410 West 55th Street, New York, NY 10019, USA.
  17. 17Veterinary Specialty Hospital of San Diego, 10435 Sorrento Valley Road, San Diego, CA 92121, USA.
  18. 18Veterinary Cancer Group of Los Angeles at City of Angels Veterinary Specialty Center, 9599 Jefferson Boulevard, Culver City, CA 90232, USA.
  19. 19Southern Arizona Veterinary Specialty and Emergency Center, 141 East Fort Lowell, Tucson, AZ 85705, USA.
  20. 20The Swim Across America Laboratory at Johns Hopkins, Baltimore, MD 21231, USA.
  1. Corresponding author. E-mail: saurabh.saha{at}gmail.com
    • * These authors contributed equally to this work.

    Altmetric

    Article usage

    Article usage: August 2014 to October 2019

    AbstractFullPdf
    Aug 2014202277941355
    Sep 20144147222462
    Oct 20143508232303
    Nov 20141623100154
    Dec 20149524072
    Jan 20151846119139
    Feb 201510376088
    Mar 201512144665
    Apr 20158715563
    May 20155972530
    Jun 20154882739
    Jul 20152572034
    Aug 2015561452
    Sep 2015513446
    Oct 2015763955
    Nov 2015575692
    Dec 20151003748
    Jan 20163271920
    Feb 20164364737
    Mar 20164401943
    Apr 20163533248
    May 20164472940
    Jun 20163682142
    Jul 20162922018
    Aug 2016302825
    Sep 20163862734
    Oct 20163671034
    Nov 20163451021
    Dec 2016215413
    Jan 20173372744
    Feb 20175782337
    Mar 20172842019
    Apr 20173221121
    May 20173231426
    Jun 2017222727
    Jul 2017491812
    Aug 20175251515
    Sep 20174851419
    Oct 20176641528
    Nov 20176754035
    Dec 2017502719
    Jan 2018407915
    Feb 20183311323
    Mar 20183401130
    Apr 20183131413
    May 20183431319
    Jun 2018300810
    Jul 201830299
    Aug 2018299124
    Sep 2018265216
    Oct 20181597404182
    Nov 20185326542
    Dec 20184456135
    Jan 20194035736
    Feb 20193885827
    Mar 20194376128
    Apr 20193185028
    May 20193233414
    Jun 20192643815
    Jul 20192223523
    Aug 20192363031
    Sep 20192034136
    Oct 2019213468