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Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis

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Science Translational Medicine  13 Aug 2014:
Vol. 6, Issue 249, pp. 249ra109
DOI: 10.1126/scitranslmed.3009377

Article Information

vol. 6 no. 249 249ra109

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication April 25, 2014
  • Accepted for publication July 15, 2014
  • .

Author Information

  1. Anne L. Fletcher1,2,3,4,*,
  2. Jessica S. Elman5,
  3. Jillian Astarita1,2,
  4. Ryan Murray5,
  5. Nima Saeidi5,
  6. Joshua D’Rozario3,
  7. Konstantin Knoblich1,
  8. Flavian D. Brown1,2,
  9. Frank A. Schildberg1,2,
  10. Janice M. Nieves1,2,
  11. Tracy S. P. Heng3,
  12. Richard L. Boyd3,,
  13. Shannon J. Turley1,2,*, and
  14. Biju Parekkadan5,6,*,
  1. 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  2. 2Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  3. 3Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia.
  4. 4School of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, UK.
  5. 5Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children, Boston, MA 02114, USA.
  6. 6Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
  1. *Corresponding author. E-mail: biju_parekkadan{at}hms.harvard.edu (B.P.); turley.shannon{at}gene.com (S.J.T.); a.fletcher{at}bham.ac.uk (A.L.F.)
    • These authors contributed equally to this work.

    • Present address: Department of Cancer Immunology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

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