Research ArticleINFERTILITY

Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection

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Science Translational Medicine  13 Aug 2014:
Vol. 6, Issue 249, pp. 249ra108
DOI: 10.1126/scitranslmed.3009071

Article Information

vol. 6 no. 249 249ra108

PubMed: 
Print ISSN: 
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History: 
  • Received for publication March 19, 2014
  • Accepted for publication May 28, 2014
  • .

Author Information

  1. Ruiying Diao1,2,3,*,
  2. Kin Lam Fok2,*,
  3. Hao Chen1,2,3,*,
  4. Mei Kuen Yu2,
  5. Yonggang Duan1,3,
  6. Chin Man Chung2,
  7. Zhao Li3,4,
  8. Hanwei Wu1,
  9. Zesong Li1,
  10. Hu Zhang3,4,
  11. Ziliang Ji3,4,
  12. Wanhua Zhen1,
  13. Chi Fai Ng5,
  14. Yaoting Gui3,
  15. Zhiming Cai1,3, and
  16. Hsiao Chang Chan2,6,
  1. 1Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Second People’s Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  2. 2Epithelial Cell Biology Research Center, Key Laboratory for Regenerative Medicine of Ministry of Education of China, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
  3. 3Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  4. 4Shantou University Medical College, Shantou 515041, China.
  5. 5Department of Surgery, Division of Urology, The Chinese University of Hong Kong, Hong Kong SAR, China.
  6. 6Sichuan University–The Chinese University of Hong Kong Joint Laboratory for Reproductive Medicine, Women’s and Children’s Hospital, Sichuan University, Sichuan 610017, China.
  1. Corresponding author. E-mail: hsiaocchan{at}cuhk.edu.hk (H.C.C.); caizhiming2000{at}163.com (Z.C.)
    • * These authors contributed equally to this work.

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