Contents
Vol 6, Issue 247
Contents
Focus
- Brain Cancer Spreads
The discovery that 20% of patients with brain cancer have circulating tumor cells breaks the dogma that these cells are confined to the brain.
- Fat Cells Gain New Identities
ASC-1, PAT2, and P2RX5 are newly identified cell-surface proteins that may distinguish brown/beige from white adipocytes in mouse and human adipose tissue (Ussar et al., this issue).
Research Articles
- A nontumorigenic variant of FGF19 treats cholestatic liver diseases
Nontumorigenic FGF19 variants represent an effective approach for the prevention and treatment of cholestatic liver diseases.
- Hematogenous dissemination of glioblastoma multiforme
Hematogenous spread of glioblastoma multiforme (GBM) might be responsible for reported extracranial metastases and transmission of GBM by organ transplantation.
- New antigens for a multicomponent blood-stage malaria vaccine
Uncharacterized proteins from the merozoite stage of Plasmodium falciparum provide new antigens for malaria blood-stage vaccine development.
- ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes
The cell surface markers ASC-1, PAT2, and P2RX5 can be used to mark and identify brown, beige, and white adipocytes in both rodents and humans.
Editors' Choice
- Autophagy Protects the Tired, the Poor, the Huddled (β Cell) Masses
Autophagy is needed to clear the toxic amyloid deposits that destroy pancreatic β cells and lead to diabetes.
- Long Noncoding RNAs in Myocardial Infarction
Peripheral blood samples can identify lncRNA changes in patients with heart attack.
- A Pillar of Hope for New Multiple Sclerosis Therapeutics
Engineered micropillar arrays enable high-throughput screening for drugs that promote remyelination in disorders such as multiple sclerosis.
- Fighting Terror with Nanotechnology
Intravenous nanoparticles with platelet-like activity improve survival after blast injury.
Retraction
