Research ArticleHIV

Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

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Science Translational Medicine  02 Jul 2014:
Vol. 6, Issue 243, pp. 243ra88
DOI: 10.1126/scitranslmed.3008992

Article Information

vol. 6 no. 243 243ra88

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 11, 2014
  • Accepted for publication April 30, 2014
  • .

Author Information

  1. Amarendra Pegu1,
  2. Zhi-yong Yang1,
  3. Jeffrey C. Boyington1,
  4. Lan Wu1,
  5. Sung-Youl Ko1,
  6. Stephen D. Schmidt1,
  7. Krisha McKee1,
  8. Wing-Pui Kong1,
  9. Wei Shi1,
  10. Xuejun Chen1,
  11. John-Paul Todd1,
  12. Norman L. Letvin1,2,*,
  13. Jinghe Huang3,
  14. Martha C. Nason4,
  15. James A. Hoxie5,
  16. Peter D. Kwong1,
  17. Mark Connors3,
  18. Srinivas S. Rao1,
  19. John R. Mascola1, and
  20. Gary J. Nabel1,
  1. 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), 40 Convent Drive, Bethesda, MD 20892, USA.
  2. 2Division of Viral Pathogenesis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, RE113, P. O. Box 15732, Boston, MA 02115, USA.
  3. 3HIV-Specific Immunity Section, Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
  4. 4Biostatistics Research Branch, NIAID, NIH, Bethesda, MD 20892, USA.
  5. 5Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  1. Corresponding author. E-mail: jmascola{at}nih.gov (J.R.M.); gary.nabel{at}sanofi.com (G.J.N.)
  • * Deceased.

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