RNAi Therapies: Drugging the Undruggable

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Science Translational Medicine  11 Jun 2014:
Vol. 6, Issue 240, pp. 240ps7
DOI: 10.1126/scitranslmed.3008362

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RNA interference (RNAi) therapy is a rapidly emerging platform for personalized cancer treatment. Recent advances in small interfering RNA delivery and target selection provide unprecedented opportunities for clinical translation. Here, we discuss these advances and present strategies for making RNAi-based therapy a viable part of cancer management.

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