11 June 2014
Vol 6, Issue 240

About The Cover

Cover image expansion

ONLINE COVER A Broad View of Cancer. A new class of imaging agents is taken up readily by nearly all human cancers, reports a new study by Weichert, Kuo, and colleagues in this issue of Science Translational Medicine. The agents, called APC analogs, were tagged with fluorescent or radioisotope labels for imaging cancer in rodent models of human tumors as well as in patient tumors, including those in hard-to-reach areas like the brain (on the cover). By being nontargeted, yet preferentially taken up by most cancers, these imaging agents are promising for broad use in the clinic. Listen to the related Podcast with John S. Kuo. [CREDIT: B. TITZ, L. T. HALL, J. S. KUO/UNIVERSITY OF WISCONSIN–MADISON]