Contents
Vol 6, Issue 235
Contents
Focus
- Neutralizing the MERS Coronavirus Threat
Human neutralizing monoclonal antibodies are candidates for prophylactic and therapeutic interventions against Middle East respiratory syndrome coronavirus (MERS-CoV) infection.
Commentary
- A Long Academic Journey
An early-career electrical engineer interviews an established biomedical engineer about translating engineering science, training future innovators, and building partnerships.
Research Articles
- T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway
Costimulatory molecules CD80/CD86 suppress osteoclast differentiation by inducing indoleamine 2,3-dioxygenase.
- CpG ODN Nanorings Induce IFNα from Plasmacytoid Dendritic Cells and Demonstrate Potent Vaccine Adjuvant Activity
Nanorings act as CpG oligodeoxynucleotide surrogates that may function as vaccine adjuvants and anticancer and antiviral agents.
Reports
- Expression of the Iron Hormone Hepcidin Distinguishes Different Types of Anemia in African Children
The iron hormone hepcidin correctly identifies African children in whom iron supplementation is most likely to be beneficial.
Editors' Choice
- Obesity Paves the Highway for Colon Cancer
Obesity “resets” enhancers of gene expression in the colon epithelium, affecting signaling pathways that initiate and promote colon cancer.
- Magnetic Resonance: It’s a Gas!
A genetically encoded magnetic resonance imaging (MRI) reporter uses bacterial proteins to encapsulate nanosized bubbles of xenon gas.
- How to Build a Better Bone Tumor
Cancer cells behave more like native tumors when they are cultured in a tissue-engineered construct designed to recapitulate important aspects of the tumor microenvironment.
- Somatic Cell Nuclear Transfer Is All Grown Up
Adult human somatic cells were reprogrammed to pluripotent stem cells by nuclear transfer to enucleated human oocytes.
