Research ArticleInfectious diseases

An Orally Available, Small-Molecule Polymerase Inhibitor Shows Efficacy Against a Lethal Morbillivirus Infection in a Large Animal Model

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Science Translational Medicine  16 Apr 2014:
Vol. 6, Issue 232, pp. 232ra52
DOI: 10.1126/scitranslmed.3008517

Article Information

vol. 6 no. 232 232ra52

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication January 13, 2014
  • Accepted for publication March 28, 2014
  • .

Author Information

  1. Stefanie A. Krumm1,*,
  2. Dan Yan1,*,
  3. Elise S. Hovingh2,
  4. Taylor J. Evers3,
  5. Theresa Enkirch2,4,
  6. G. Prabhakar Reddy3,
  7. Aiming Sun3,
  8. Manohar T. Saindane3,
  9. Richard F. Arrendale3,
  10. George Painter3,5,
  11. Dennis C. Liotta6,
  12. Michael G. Natchus3,
  13. Veronika von Messling2,4 and
  14. Richard K. Plemper1,7,
  1. 1Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
  2. 2Veterinary Medicine Division, Paul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines, 63225 Langen, Germany.
  3. 3Emory Institute for Drug Development, Emory University, Atlanta, GA 30322, USA.
  4. 4Emerging Infectious Disease Program, Duke-NUS Graduate Medical School, Singapore 169857, Singapore.
  5. 5Drug Innovation Ventures at Emory, Atlanta, GA 30309, USA.
  6. 6Department of Chemistry, Emory University, Atlanta, GA 30322, USA.
  7. 7Department of Pediatrics, Emory University, Atlanta, GA 30322, USA.
  1. Corresponding author. E-mail: rplemper{at}gsu.edu
  • * These authors contributed equally to this work.

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