Research ArticleAutoimmunity

Pituitary Expression of CTLA-4 Mediates Hypophysitis Secondary to Administration of CTLA-4 Blocking Antibody

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Science Translational Medicine  02 Apr 2014:
Vol. 6, Issue 230, pp. 230ra45
DOI: 10.1126/scitranslmed.3008002

Article Information

vol. 6 no. 230 230ra45

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 11, 2013
  • Accepted for publication February 6, 2014
  • .

Author Information

  1. Shintaro Iwama1,2,
  2. Alessandra De Remigis1,
  3. Margaret K. Callahan3,4,
  4. Susan F. Slovin3,4,
  5. Jedd D. Wolchok3,4,5 and
  6. Patrizio Caturegli1,6,*
  1. 1Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA.
  2. 2Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
  3. 3Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  4. 4Weill Cornell Medical College, New York, NY 10065, USA.
  5. 5Ludwing Institute for Cancer Research, New York, NY 10065, USA.
  6. 6Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
  1. *Corresponding author. E-mail: pcat{at}jhmi.edu

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