Research ArticleRetinal Disease

IL-18 Attenuates Experimental Choroidal Neovascularization as a Potential Therapy for Wet Age-Related Macular Degeneration

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Science Translational Medicine  02 Apr 2014:
Vol. 6, Issue 230, pp. 230ra44
DOI: 10.1126/scitranslmed.3007616

Article Information

vol. 6 no. 230 230ra44

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 17, 2013
  • Accepted for publication February 13, 2014
  • .

Author Information

  1. Sarah L. Doyle1,2,*,
  2. Ema Ozaki3,
  3. Kiva Brennan4,
  4. Marian M. Humphries3,
  5. Kelly Mulfaul1,2,
  6. James Keaney3,
  7. Paul F. Kenna3,5,
  8. Arvydas Maminishkis6,
  9. Anna-Sophia Kiang3,
  10. Sean P. Saunders7,
  11. Emily Hams7,
  12. Ed C. Lavelle4,
  13. Clair Gardiner4,
  14. Padraic G. Fallon7,
  15. Peter Adamson8,
  16. Peter Humphries3 and
  17. Matthew Campbell3,*
  1. 1Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin 2, Ireland.
  2. 2National Children’s Research Centre, Our Lady’s Children’s Hospital, Crumlin, Dublin 12, Ireland.
  3. 3Ocular Genetics Unit, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
  4. 4School of Biochemistry and Immunology, Immunology Research Centre, Trinity Biomedical Sciences Institute, Trinity College, Dublin 2, Ireland.
  5. 5Research Foundation, Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, Ireland.
  6. 6National Eye Institute, National Institutes of Health, Bethesda, MD 20892–0001, USA.
  7. 7Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland.
  8. 8Ophthiris Discovery Performance Unit, GlaxoSmithKline, Stevenage SG1 2NY, UK.
  1. *Corresponding author. E-mail: matthew.campbell{at}tcd.ie (M.C.); sarah.doyle{at}tcd.ie (S.L.D.)

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