Research ArticlePERIODONTITIS

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17–Driven Inflammatory Bone Loss

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Science Translational Medicine  26 Mar 2014:
Vol. 6, Issue 229, pp. 229ra40
DOI: 10.1126/scitranslmed.3007696

Article Information

vol. 6 no. 229 229ra40

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 30, 2013
  • Accepted for publication February 13, 2014
  • .

Author Information

  1. Niki M. Moutsopoulos1,*,
  2. Joanne Konkel2,
  3. Mojgan Sarmadi1,
  4. Mehmet A. Eskan3,
  5. Teresa Wild1,
  6. Nicolas Dutzan1,
  7. Loreto Abusleme1,
  8. Camille Zenobia4,
  9. Kavita B. Hosur4,
  10. Toshiharu Abe4,
  11. Gulbu Uzel5,
  12. WanJun Chen2,
  13. Triantafyllos Chavakis6,
  14. Steven M. Holland5 and
  15. George Hajishengallis4,*
  1. 1National Institute of Dental and Craniofacial Research, Oral Immunity and Infection Unit, Oral and Pharyngeal Cancer Branch, National Institutes of Health, Bethesda, MD 20892, USA.
  2. 2National Institute of Dental and Craniofacial Research, Mucosal Immunology Section, Oral and Pharyngeal Cancer Branch, National Institutes of Health, Bethesda, MD 20892, USA.
  3. 3Oral Health and Systemic Disease Research Group, University of Louisville School of Dentistry, Louisville, KY 40202, USA.
  4. 4Department of Microbiology, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA.
  5. 5National Institute of Allergy and Infectious Diseases, Laboratory of Clinical Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  6. 6Department of Medicine, Department of Clinical Pathobiochemistry, and Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307 Dresden, Germany.
  1. *Corresponding author: E-mail: nmoutsop{at}mail.nih.gov (N.M.); geoh{at}upenn.edu (G.H.)

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