Research ArticleHypertension

Intestinal Inhibition of the Na+/H+ Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na+ Uptake in Humans

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Science Translational Medicine  12 Mar 2014:
Vol. 6, Issue 227, pp. 227ra36
DOI: 10.1126/scitranslmed.3007790

Article Information

vol. 6 no. 227 227ra36

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 14, 2013
  • Accepted for publication February 10, 2014
  • .

Author Information

  1. Andrew G. Spencer1,
  2. Eric D. Labonte1,
  3. David P. Rosenbaum1,
  4. Craig F. Plato2,
  5. Christopher W. Carreras1,
  6. Michael R. Leadbetter1,
  7. Kenji Kozuka1,
  8. Jill Kohler1,
  9. Samantha Koo-McCoy1,
  10. Limin He1,
  11. Noah Bell1,
  12. Jocelyn Tabora1,
  13. Kristin M. Joly2,
  14. Marc Navre1,
  15. Jeffrey W. Jacobs1 and
  16. Dominique Charmot1,*
  1. 1Ardelyx Inc., Fremont, CA 94555, USA.
  2. 2Plato BioPharma Inc., Westminster, CO 80021, USA.
  1. *Corresponding author. E-mail: dcharmot{at}ardelyx.com

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