Research ArticleVascular Biology

TGF-β Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling

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Science Translational Medicine  12 Mar 2014:
Vol. 6, Issue 227, pp. 227ra34
DOI: 10.1126/scitranslmed.3006927

Article Information

vol. 6 no. 227 227ra34

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 3, 2013
  • Accepted for publication February 21, 2014
  • .

Author Information

  1. Brian C. Cooley1,*,,
  2. Jose Nevado2,3,,
  3. Jason Mellad4,,
  4. Dan Yang3,
  5. Cynthia St. Hilaire3,
  6. Alejandra Negro3,
  7. Fang Fang3,
  8. Guibin Chen3,
  9. Hong San3,
  10. Avram D. Walts3,
  11. Robin L. Schwartzbeck3,
  12. Brandi Taylor3,
  13. Jan D. Lanzer3,
  14. Andrew Wragg3,4,
  15. Abdalla Elagha3,5,
  16. Leilani E. Beltran3,
  17. Colin Berry3,6,
  18. Robert Feil7,
  19. Renu Virmani8,
  20. Elena Ladich8,
  21. Jason C. Kovacic3,9 and
  22. Manfred Boehm3,
  1. 1Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
  2. 2National Institutes of Health–University of the Philippines College of Medicine, Manila 1000, Philippines.
  3. 3Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  4. 4William Harvey Research Institute, Barts and the London NHS Trust, London EC1M 6BQ, UK.
  5. 5Cardiovascular Department, Faculty of Medicine, Cairo University, Cairo 11559, Egypt.
  6. 6Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, Scotland, UK.
  7. 7Interfaculty Institute of Biochemistry, Universität Tübingen, 72074 Tübingen, Germany.
  8. 8CVPath Institute Inc., Gaithersburg, MD 20878, USA.
  9. 9The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  1. Corresponding author. E-mail: boehmm{at}nhlbi.nih.gov
  • * Present address: Department of Pathology and McAllister Heart Institute, University of North Carolina, Chapel Hill, NC 27599, USA.

  • These authors contributed equally to this work.

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