Research ArticleCancer

Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer

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Science Translational Medicine  19 Feb 2014:
Vol. 6, Issue 224, pp. 224ra26
DOI: 10.1126/scitranslmed.3007947

Article Information

vol. 6 no. 224 224ra26

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 4, 2013
  • Accepted for publication December 27, 2013
  • .

Author Information

  1. Sandra Misale1,2,*,
  2. Sabrina Arena1,2,*,
  3. Simona Lamba1,2,
  4. Giulia Siravegna1,2,
  5. Alice Lallo1,2,
  6. Sebastijan Hobor2,
  7. Mariangela Russo1,2,
  8. Michela Buscarino2,
  9. Luca Lazzari2,3,
  10. Andrea Sartore-Bianchi4,
  11. Katia Bencardino4,
  12. Alessio Amatu4,
  13. Calogero Lauricella5,
  14. Emanuele Valtorta5,
  15. Salvatore Siena4,
  16. Federica Di Nicolantonio1,2 and
  17. Alberto Bardelli1,2,3,
  1. 1Department of Oncology, University of Torino, 10060 Candiolo, Torino, Italy.
  2. 2Institute for Cancer Research and Treatment, 10060 Candiolo, Torino, Italy.
  3. 3Italian Foundation for Cancer Research Institute of Molecular Oncology, 20139 Milano, Italy.
  4. 4Niguarda Cancer Center, Ospedale Niguarda Ca’ Granda, 20162 Milano, Italy
  5. 5Division of Pathology, Niguarda Cancer Center, Ospedale Niguarda Ca’ Granda, 20162 Milano, Italy.
  1. Corresponding author. E-mail: alberto.bardelli{at}unito.it
  • * These authors contributed equally to this work.

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