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Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

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Science Translational Medicine  19 Feb 2014:
Vol. 6, Issue 224, pp. 224ra25
DOI: 10.1126/scitranslmed.3008226

Article Information

vol. 6 no. 224 224ra25

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 9, 2013
  • Accepted for publication January 24, 2014
  • .

Author Information

  1. Marco L. Davila1,
  2. Isabelle Riviere1,2,3,4,
  3. Xiuyan Wang4,
  4. Shirley Bartido4,
  5. Jae Park1,
  6. Kevin Curran5,
  7. Stephen S. Chung1,
  8. Jolanta Stefanski4,
  9. Oriana Borquez-Ojeda4,
  10. Malgorzata Olszewska4,
  11. Jinrong Qu4,
  12. Teresa Wasielewska4,
  13. Qing He4,
  14. Mitsu Fink4,
  15. Himaly Shinglot4,
  16. Maher Youssif4,
  17. Mark Satter4,
  18. Yongzeng Wang4,
  19. James Hosey4,
  20. Hilda Quintanilla1,
  21. Elizabeth Halton1,
  22. Yvette Bernal1,
  23. Diana C. G. Bouhassira2,
  24. Maria E. Arcila6,
  25. Mithat Gonen7,
  26. Gail J. Roboz8,
  27. Peter Maslak1,
  28. Dan Douer1,
  29. Mark G. Frattini9,
  30. Sergio Giralt1,2,
  31. Michel Sadelain1,2,3,* and
  32. Renier Brentjens1,2,3,*
  1. 1Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  2. 2Center for Cell Engineering, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  3. 3Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  4. 4Cell Therapy and Cell Engineering Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  5. 5Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  6. 6Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  7. 7Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
  8. 8Leukemia Service, NewYork-Presbyterian/Weill Cornell, New York, NY 10065, USA.
  9. 9Leukemia Service, NewYork-Presbyterian/Columbia, New York, NY 10032, USA.
  1. *Corresponding author. E-mail: brentjer{at}mskcc.org (R.B.); m-sadelain{at}ski.mskcc.org (M.S.)

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