Research ArticleAlzheimer’s Disease

Lysosomal Sorting of Amyloid-β by the SORLA Receptor Is Impaired by a Familial Alzheimer’s Disease Mutation

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Science Translational Medicine  12 Feb 2014:
Vol. 6, Issue 223, pp. 223ra20
DOI: 10.1126/scitranslmed.3007747

Article Information

vol. 6 no. 223 223ra20

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 8, 2013
  • Accepted for publication January 24, 2014
  • .

Author Information

  1. Safak Caglayan1,
  2. Shizuka Takagi-Niidome2,
  3. Fan Liao3,4,
  4. Anne-Sophie Carlo1,
  5. Vanessa Schmidt1,
  6. Tilman Burgert1,
  7. Yu Kitago2,
  8. Ernst-Martin Füchtbauer5,
  9. Annette Füchtbauer5,
  10. David M. Holtzman3,4,
  11. Junichi Takagi2,* and
  12. Thomas E. Willnow1,*
  1. 1Max-Delbrueck-Center for Molecular Medicine, 13125 Berlin, Germany.
  2. 2Institute for Protein Research, Osaka University, Osaka 565-0871, Japan.
  3. 3Department of Neurology, Washington University, St. Louis, MO 63110, USA.
  4. 4Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA.
  5. 5Department of Molecular Biology, Aarhus University, 8000 Aarhus, Denmark.
  1. *Corresponding author. E-mail: willnow{at}mdc-berlin.de (T.E.W.); takagi{at}protein.osaka-u.ac.jp (J.T.)

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