Research ArticleCancer

Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice

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Science Translational Medicine  01 Jan 2014:
Vol. 6, Issue 217, pp. 217ra2
DOI: 10.1126/scitranslmed.3007048

Article Information

vol. 6 no. 217 217ra2

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 16, 2013
  • Accepted for publication November 5, 2013
  • .

Author Information

  1. Amy Brock1,*,,
  2. Silva Krause2,*,
  3. Hu Li1,*,,
  4. Marek Kowalski1,
  5. Michael S. Goldberg3,
  6. James J. Collins1,4 and
  7. Donald E. Ingber1,2,§
  1. 1Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  2. 2Vascular Biology Program, Boston Children’s Hospital and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
  3. 3Dana-Farber Cancer Research Institute, Harvard Medical School, Boston, MA 02115, USA.
  4. 4Howard Hughes Medical Institute, Boston University, Boston, MA 02115, USA.
  1. §Corresponding author. E-mail: don.ingber{at}wyss.harvard.edu
  • * These authors contributed equally to this work.

  • Present address: Department of Biomedical Engineering and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.

  • Present address: Center for Individualized Medicine, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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