Contents
Vol 6, Issue 217
Editors' Choice
- Hydrogen Fuels Cells in the Gut
Salmonella uses the hydrogen produced by resident gut microbes to get a boost in early infection.
- Fibroblasts in Colon Cancer: Turned Traitor by Chemotherapy
A pathway for protumor fibroblast behavior is promoted by chemotherapy.
Editorial
- Academia and Big Pharma United
Sweden’s premier medical university, the Karolinska Institutet, and the big pharma AstraZeneca have established an integrated cardio-metabolic research center with academic and pharma scientists working side by side.
Research Articles
- The Circulating Proteinase Inhibitor α-1 Antitrypsin Regulates Neutrophil Degranulation and Autoimmunity
α-1 antitrypsin regulates neutrophil-driven autoimmunity.
- Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice
Silencing of HoxA1 with nanoparticle siRNA prevented loss of hormone receptor expression, suppressed cell proliferation, and reduced mammary tumor incidence in mice.
- Genetic Engineering of Hematopoiesis for Targeted IFN-α Delivery Inhibits Breast Cancer Progression
Inhibition of primary and metastatic breast cancer by targeted delivery of interferon-α by tumor-infiltrating monocytes.