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CD4+ T Cell Autoimmunity to Hypocretin/Orexin and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsy

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Science Translational Medicine  18 Dec 2013:
Vol. 5, Issue 216, pp. 216ra176
DOI: 10.1126/scitranslmed.3007762

Article Information

vol. 5 no. 216 216ra176

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication October 9, 2013
  • Accepted for publication November 27, 2013
  • .

Author Information

  1. Alberto K. De la Herrán-Arita1,*,
  2. Birgitte Rahbek Kornum1,2,*,
  3. Josh Mahlios1,
  4. Wei Jiang3,
  5. Ling Lin1,
  6. Tieying Hou3,
  7. Claudia Macaubas3,
  8. Mali Einen1,
  9. Giuseppe Plazzi4,
  10. Catherine Crowe5,
  11. Evan W. Newell6,
  12. Mark M. Davis6,
  13. Elizabeth D. Mellins3,6,*, and
  14. Emmanuel Mignot1,6,*,
  1. 1Center for Sleep Sciences and Medicine, Stanford School of Medicine, Palo Alto, CA 94304, USA.
  2. 2Molecular Sleep Lab, Department of Diagnostics, and Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Glostrup Hospital, 2600 Glostrup, Denmark.
  3. 3Department of Pediatrics, Stanford School of Medicine, Palo Alto, CA 94305, USA.
  4. 4IRCCS Institute of Neurological Sciences and Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna 40123, Italy.
  5. 5Mater Private Sleep Laboratory, Dublin 7, Ireland.
  6. 6Program in Immunology, Stanford School of Medicine, Palo Alto, CA 94305, USA.
  1. Corresponding author. E-mail: mignot{at}stanford.edu (E.M.); mellins{at}stanford.edu (E.D.M.)
  • * These authors contributed equally to this work.

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