Contents
Vol 5, Issue 213
State of the Art Review
- TB or Not TB: That Is No Longer the Question
The study of TB in humans is essential for understanding the disease, as well as for developing better treatment and prevention strategies.
Erratum
Editorial
- The Affordable Care Act as Translational Research
The Affordable Care Act is the biggest U.S. health care policy experiment since Medicare and deserves our support.
Research Articles
- HIV-1 Vpr Induces Adipose Dysfunction in Vivo Through Reciprocal Effects on PPAR/GR Co-Regulation
HIV-1 Vpr induces the cardinal metabolic defects of HIV-associated lipodystrophy and hepatosteatosis in vivo.
- Real-Time, Aptamer-Based Tracking of Circulating Therapeutic Agents in Living Animals
An aptamer-based biosensor continuously measures the concentration of drug molecules in the blood of living animals and in patient samples.
- The Tongue Enables Computer and Wheelchair Control for People with Spinal Cord Injury
Individuals with severe spinal cord injury control a computer and powered wheelchair by using a wireless tongue-operated assistive technology called the Tongue Drive System.
- Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery
Nanoparticles targeted to the neonatal Fc receptor cross the intestinal epithelium and reach systemic circulation after oral administration.
Editors' Choice
- Stenting for Stroke
Aggressive medical management demonstrates benefit over stenting for high-risk patients with intracranial stenosis.
- Waking a Sleeping Giant…on Purpose?
Rousing and treating dormant tumors before their escape from the innate immune system may prevent tumor recurrence.
- Testosterone Replacement Leaving Men Heartbroken
Testosterone treatment has recently gained popularity, but increased mortality and cardiovascular events are emerging concerns.
- Too Much of a Good Thing?
Overexpression of the synaptic scaffolding protein SHANK3 is associated with hyperactive behavior and an imbalance between synaptic excitation and inhibition.
