Research ArticleAlzheimer’s Disease

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

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Science Translational Medicine  20 Nov 2013:
Vol. 5, Issue 212, pp. 212ra161
DOI: 10.1126/scitranslmed.3007000

Article Information

vol. 5 no. 212 212ra161

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 10, 2013
  • Accepted for publication October 16, 2013
  • .

Author Information

  1. Eloise Hudry1,
  2. Jonathan Dashkoff1,
  3. Alysson D. Roe1,
  4. Shuko Takeda1,
  5. Robert M. Koffie1,
  6. Tadafumi Hashimoto1,
  7. Maria Scheel2,
  8. Tara Spires-Jones1,
  9. Michal Arbel-Ornath1,
  10. Rebecca Betensky3,
  11. Beverly L. Davidson2 and
  12. Bradley T. Hyman1,*
  1. 1MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  2. 2Department of Internal Medicine, Neurology and Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
  3. 3Harvard School of Public Health, Boston, MA 02115, USA.
  1. *Corresponding author. E-mail: bhyman{at}mgh.harvard.edu

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