06 November 2013
Vol 5, Issue 210
  • Review

    • Personalized Neuroprosthetics

      Personalized neuroprosthetics is the synergy between accurate diagnosis, integrated development of neurotechnology, and patient-specific treatment design “to help the brain help itself” in nervous system disorders.

  • Perspectives

  • Editorial

  • Research Articles

  • Editors' Choice

    • Money for Robots

      Co-robots might be our new best friends if a U.S. federal funding initiative is successful.

    • Targeting ER Stress in Parkinson's Disease

      α-Synuclein–mediated toxicity in Parkinson’s disease involves nitrosative stress, endoplasmic reticulum (ER) stress, and impaired ER function, which can be rescued in vitro with a small molecule.

    • A Chance of a Cure for HIV

      In an HIV-infected infant who received antiretroviral therapy from 30 hours until 18 months of age, HIV virus was undetectable months after therapy was stopped.

    • Silencing the Sounds of Hypertrophic Cardiomyopathy

      An RNA interference strategy of allele specific silencing in the heart identifies a potential new therapy for patients with hypertrophic cardiomyopathy.

About The Cover

Cover image expansion

ONLINE COVER Special Issue: Robotics & Neuroprosthetics. To outfit the human body, researchers are designing neuroprosthetic or robotic technologies that tap into either the central nervous system [CNS, brain (in pink) and spinal cord (in yellow)] or the peripheral nervous system—nerves (in yellow) that connect the CNS to the rest of the body. These 21st-century fashions can help individuals recover lost sensory and motor functions. In this special issue, we present Reviews and Perspectives that discuss the latest in such neurotechnology, from advancing personalized neuroprosthetics to improving lower-limb robotics to translating the brain-computer interface. The binary background emphasizes the central role of computation in precisely controlling robotics and neuroprosthetics. Also in this issue are two related research articles by Ifft et al. and Chew et al. [CREDIT: ERAXION/ISTOCKPHOTO]