Contents
Vol 5, Issue 210
Review
- Personalized Neuroprosthetics
Personalized neuroprosthetics is the synergy between accurate diagnosis, integrated development of neurotechnology, and patient-specific treatment design “to help the brain help itself” in nervous system disorders.
Perspectives
- Realizing the Promise of Robotic Leg Prostheses
Robotic prosthetic legs promise to restore healthy biomechanical function if they are well interfaced to the human neuromuscular control system.
- Fighting Blindness with Microelectronics
Electronic retinal implants for treating inherited diseases of retinal degeneration have entered the clinic, but many hurdles remain to achieving full vision.
- Translating the Brain-Machine Interface
Brain-machine interfaces hold promise for the recovery of sensory and motor functions, but translational challenges remain.
Editorial
- Smaller, Softer, Safer, Smarter Robots
Advances in robotics aim to extend physician capabilities.
Research Articles
- A Brain-Machine Interface Enables Bimanual Arm Movements in Monkeys
Large-scale recordings from monkey cortex enabled simultaneous control of two avatar arms through a brain-machine interface.
- A Microchannel Neuroprosthesis for Bladder Control After Spinal Cord Injury in Rat
An electronic interface for recording and stimulating nerves that innervate the bladder helps to restore normal bladder function in rats with spinal cord injury.
Editors' Choice
- Money for Robots
Co-robots might be our new best friends if a U.S. federal funding initiative is successful.
- Graph Theory Modeling for Diagnosing Presymptomatic Alzheimer's Disease
Graph theory modeling of brain MRI images reveals early, presymptomatic signs of Alzheimer's disease.
- Targeting ER Stress in Parkinson's Disease
α-Synuclein–mediated toxicity in Parkinson’s disease involves nitrosative stress, endoplasmic reticulum (ER) stress, and impaired ER function, which can be rescued in vitro with a small molecule.
- A Chance of a Cure for HIV
In an HIV-infected infant who received antiretroviral therapy from 30 hours until 18 months of age, HIV virus was undetectable months after therapy was stopped.
- Silencing the Sounds of Hypertrophic Cardiomyopathy
An RNA interference strategy of allele specific silencing in the heart identifies a potential new therapy for patients with hypertrophic cardiomyopathy.
