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Research ArticleAging
Sulfate Metabolites Provide an Intracellular Pool for Resveratrol Generation and Induce Autophagy with Senescence
- Ketan R. Patel1,
- Catherine Andreadi1,
- Robert G. Britton1,
- Emma Horner-Glister1,
- Ankur Karmokar1,
- Stewart Sale1,
- Victoria A. Brown1,
- Dean E. Brenner2,
- Rajinder Singh1,
- William P. Steward1,
- Andreas J. Gescher1 and
- Karen Brown1,*
- 1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
- 2Departments of Internal Medicine and Pharmacology, University of Michigan Medical School and Veterans Affairs Medical Center, Ann Arbor, MI 48109–5930, USA.
- ↵*Corresponding author. E-mail: kb20{at}le.ac.uk.
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Science Translational Medicine 02 Oct 2013:
Vol. 5, Issue 205, pp. 205ra133
DOI: 10.1126/scitranslmed.3005870
Vol. 5, Issue 205, pp. 205ra133
DOI: 10.1126/scitranslmed.3005870
Ketan R. Patel
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Catherine Andreadi
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Robert G. Britton
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Emma Horner-Glister
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Ankur Karmokar
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Stewart Sale
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Victoria A. Brown
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Dean E. Brenner
2Departments of Internal Medicine and Pharmacology, University of Michigan Medical School and Veterans Affairs Medical Center, Ann Arbor, MI 48109–5930, USA.
Rajinder Singh
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
William P. Steward
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Andreas J. Gescher
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
Karen Brown
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE2 7LX, UK.
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