Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

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  Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

  By Ishita Das, Joo-Min Park, Jung H. Shin, Soo Kyeong Jeon, Hernan Lorenzi, David J. Linden, Paul F. Worley, Roger H. Reeves

  Science Translational Medicine04 Sep 2013 : 201ra120

  In a mouse model of Down syndrome, treatment with a Sonic hedgehog agonist on the day of birth normalized cerebellar structure and improved learning and memory.

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  Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

  By Ishita Das, Joo-Min Park, Jung H. Shin, Soo Kyeong Jeon, Hernan Lorenzi, David J. Linden, Paul F. Worley, Roger H. Reeves

  Science Translational Medicine04 Sep 2013 : 201ra120

  In a mouse model of Down syndrome, treatment with a Sonic hedgehog agonist on the day of birth normalized cerebellar structure and improved learning and memory.

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