Research ArticleDown Syndrome

Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

See allHide authors and affiliations

Science Translational Medicine  04 Sep 2013:
Vol. 5, Issue 201, pp. 201ra120
DOI: 10.1126/scitranslmed.3005983

Article Information

vol. 5 no. 201 201ra120

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 21, 2013
  • Accepted for publication July 8, 2013
  • .

Author Information

  1. Ishita Das1,
  2. Joo-Min Park2,3,
  3. Jung H. Shin4,
  4. Soo Kyeong Jeon2,
  5. Hernan Lorenzi1,*,
  6. David J. Linden2,
  7. Paul F. Worley2 and
  8. Roger H. Reeves1,
  1. 1Department of Physiology and Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  2. 2Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  3. 3Department of Physiology, Jeju National University School of Medicine, Jeju 690-756, South Korea.
  4. 4Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD 20857, USA.
  1. Corresponding author. E-mail: rreeves{at}jhmi.edu
  • * Present address: The J. Craig Venter Institute, Rockville, MD 20850, USA.

Altmetric

Article usage

Article usage: August 2013 to January 2021

AbstractFullPdf
Aug 20137511
Sep 201315060652864
Oct 20132061109176
Nov 2013119858100
Dec 20136232557
Jan 20146522445
Feb 201483560102
Mar 2014139283176
Apr 20148434462
May 20145192635
Jun 20143281122
Jul 2014284726
Aug 20143302137
Sep 20143293121
Oct 20142663126
Nov 20142012925
Dec 20143293120
Jan 20154604947
Feb 20152191919
Mar 20152991821
Apr 20152983337
May 20152642532
Jun 20151461917
Jul 20151331030
Aug 201539913
Sep 201523820
Oct 2015262415
Nov 201521411
Dec 2015521812
Jan 20162191026
Feb 20161541515
Mar 20161591217
Apr 20161681814
May 2016178619
Jun 20162661012
Jul 201616494
Aug 20161111411
Sep 20161841017
Oct 201613847
Nov 2016174117
Dec 201614949
Jan 201712626
Feb 20171541119
Mar 2017165519
Apr 20171301319
May 2017154717
Jun 2017106111
Jul 2017121613
Aug 201710167
Sep 2017152511
Oct 20171551417
Nov 201712818
Dec 201711078
Jan 20188835
Feb 201868511
Mar 201810855
Apr 201811716
May 201810783
Jun 201815145
Jul 20181191112
Aug 201885116
Sep 201810397
Oct 2018133137
Nov 2018107138
Dec 20189422
Jan 201977104
Feb 2019107204
Mar 2019911810
Apr 201982127
May 201963135
Jun 20194540
Jul 20197872
Aug 201961181
Sep 201931136
Oct 2019502712
Nov 2019983823
Dec 2019571613
Jan 202068217
Feb 20205230
Mar 20206764
Apr 20207098
May 20205097
Jun 20203265
Jul 20203152
Aug 20203463
Sep 20205089
Oct 202071156
Nov 202053106
Dec 202058263
Jan 20213862

Stay Connected to Science Translational Medicine