04 September 2013
Vol 5, Issue 201

About The Cover

Cover image expansion

ONLINE COVER Tumor-Spotting. Brain surgeons identify tumors by appearance and by touch and thus, can accidentally remove healthy tissue or leave tumor behind. To make tumors clearly visible during surgery, Ji, Orringer, and colleagues devised a stimulated Raman scattering (SRS) microscopy method that distinguishes protein-rich tumor (false-colored blue) from lipid-rich healthy brain (in green). The authors used SRS microscopy to spot human cancer tissue both in mice and in brain samples from a patient with glioblastoma. [CREDIT: M. JI/HARVARD UNIVERSITY; D. A. ORRINGER/UNIVERSITY OF MICHIGAN]