Research ArticleEbola
Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail
- James Pettitt1,*,
- Larry Zeitlin2,*,†,
- Do H. Kim2,
- Cara Working3,
- Joshua C. Johnson1,
- Ognian Bohorov2,
- Barry Bratcher3,
- Ernie Hiatt3,
- Steven D. Hume3,
- Ashley K. Johnson3,
- Josh Morton3,
- Michael H. Pauly2,
- Kevin J. Whaley2,
- Michael F. Ingram1,
- Ashley Zovanyi1,
- Megan Heinrich1,
- Ashley Piper1,
- Justine Zelko1 and
- Gene G. Olinger1,†
- 1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
- 2Mapp Biopharmaceutical Inc., 6160 Lusk Boulevard, #C105, San Diego, CA 92121, USA.
- 3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
- ↵†Corresponding author. E-mail: gene.olinger{at}us.army.mil (G.G.O.); larry.zeitlin{at}mappbio.com (L.Z.)
-
↵* These authors contributed equally to this work.
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Science Translational Medicine 21 Aug 2013:
Vol. 5, Issue 199, pp. 199ra113
DOI: 10.1126/scitranslmed.3006608
Vol. 5, Issue 199, pp. 199ra113
DOI: 10.1126/scitranslmed.3006608
James Pettitt
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Larry Zeitlin
2Mapp Biopharmaceutical Inc., 6160 Lusk Boulevard, #C105, San Diego, CA 92121, USA.
Do H. Kim
2Mapp Biopharmaceutical Inc., 6160 Lusk Boulevard, #C105, San Diego, CA 92121, USA.
Cara Working
3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
Joshua C. Johnson
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Ognian Bohorov
2Mapp Biopharmaceutical Inc., 6160 Lusk Boulevard, #C105, San Diego, CA 92121, USA.
Barry Bratcher
3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
Ernie Hiatt
3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
Steven D. Hume
3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
Ashley K. Johnson
3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
Josh Morton
3Kentucky BioProcessing, LLC, 3700 Airpark Drive, Owensboro, KY 42301, USA.
Michael H. Pauly
2Mapp Biopharmaceutical Inc., 6160 Lusk Boulevard, #C105, San Diego, CA 92121, USA.
Kevin J. Whaley
2Mapp Biopharmaceutical Inc., 6160 Lusk Boulevard, #C105, San Diego, CA 92121, USA.
Michael F. Ingram
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Ashley Zovanyi
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Megan Heinrich
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Ashley Piper
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Justine Zelko
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
Gene G. Olinger
1Division of Virology, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.
