Contents
Vol 5, Issue 198
Contents
Editorial
- Regulating Genomics: Time for a Broader Vision
Regulators must consider the potential benefits of using genomic information to advance clinical medicine.
Focus
- Making Waves in Consciousness Research
A new strategy for quantifying consciousness may have broad applications in the clinic and the lab.
Research Articles
- A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior
A theory-derived index of consciousness, which quantifies the complexity of the brain’s response to a stimulus, measures the level of consciousness in awake, sleeping, anesthetized, and brain-damaged subjects.
- Fetal Urinary Peptides to Predict Postnatal Outcome of Renal Disease in Fetuses with Posterior Urethral Valves (PUV)
Peptides found in fetal urine predict end-stage renal disease in patients with a congenital abnormality of the kidney and urinary tract.
- Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis
Antigenic variation promotes neutralizing antibodies to both seasonal and pandemic influenza A strains in humans.
- Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate
Metabolic imaging with hyperpolarized pyruvate was used to safely and noninvasively visualize prostate tumors in patients.
Editors' Choice
- A Fat Chance for Antidepressants
Antidepressants inhibit acid sphingomyelinase to influence neurogenesis and depression-like behaviors.
- A Primate Model for Autism
Pregnant macaques given human autoantibodies against fetal brain proteins results in autism-like behavior patterns and increased brain volume in the offspring.
- Drugs and Bugs
Knowing how a specific bacterial strain inactivates the cardiac drug digoxin can pinpoint new biomarkers for tailoring therapy.
- A New Drug on the Block
A new synthetic compound with a different mechanism of action from traditional tuberculosis (TB) drugs is safe and effective in a mouse model of TB.
- Casting Infection as Cancer’s Best Friend
Infection in cancer patients may increase the risk of metastasis.