Research ArticleImmunotherapy

Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells

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Science Translational Medicine  07 Aug 2013:
Vol. 5, Issue 197, pp. 197ra103
DOI: 10.1126/scitranslmed.3006034

Article Information

vol. 5 no. 197 197ra103

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 27, 2013
  • Accepted for publication July 1, 2013
  • .

Author Information

  1. Brian J. Cameron1,
  2. Andrew B. Gerry2,*,
  3. Joseph Dukes1,*,
  4. Jane V. Harper1,*,
  5. Vivekanandan Kannan1,
  6. Frayne C. Bianchi1,
  7. Francis Grand1,
  8. Joanna E. Brewer2,
  9. Minnal Gupta3,
  10. Gabriela Plesa3,
  11. Giovanna Bossi1,
  12. Annelise Vuidepot1,
  13. Alex S. Powlesland1,
  14. Alison Legg1,
  15. Katherine J. Adams2,
  16. Alan D. Bennett2,
  17. Nicholas J. Pumphrey2,
  18. Daniel D. Williams2,
  19. Gwendolyn Binder-Scholl2,
  20. Irina Kulikovskaya3,
  21. Bruce L. Levine3,
  22. James L. Riley4,
  23. Angel Varela-Rohena4,
  24. Edward A. Stadtmauer3,
  25. Aaron P. Rapoport5,
  26. Gerald P. Linette6,
  27. Carl H. June3,
  28. Namir J. Hassan1,
  29. Michael Kalos3 and
  30. Bent K. Jakobsen1,2,
  1. 1Immunocore Ltd., 57c Milton Park, Jubilee Avenue, Abingdon, OX14 4RX, UK.
  2. 2Adaptimmune Ltd., 57c Milton Park, Jubilee Avenue, Abingdon, OX14 4RX, UK.
  3. 3Abramson Cancer Center and Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  4. 4Abramson Cancer Center and Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  5. 5The Greenebaum Cancer Center, University of Maryland, Baltimore, MD 21201, USA.
  6. 6Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA.
  1. Corresponding author. E-mail: bent.jakobsen{at}immunocore.com
  • * These authors contributed equally to this work.

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