Research ArticleGene Therapy

Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys

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Science Translational Medicine  17 Jul 2013:
Vol. 5, Issue 194, pp. 194ra92
DOI: 10.1126/scitranslmed.3005795

Article Information

vol. 5 no. 194 194ra92

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication January 28, 2013
  • Accepted for publication May 10, 2013
  • .

Author Information

  1. Federico Mingozzi1,*,,
  2. Xavier M. Anguela1,2,
  3. Giulia Pavani1,
  4. Yifeng Chen1,2,
  5. Robert J. Davidson1,
  6. Daniel J. Hui1,
  7. Mustafa Yazicioglu1,
  8. Liron Elkouby1,2,
  9. Christian J. Hinderer1,3,
  10. Armida Faella1,
  11. Carolann Howard1,
  12. Alex Tai1,
  13. Gregory M. Podsakoff1,
  14. Shangzhen Zhou1,
  15. Etiena Basner-Tschakarjan1,
  16. John Fraser Wright1,4 and
  17. Katherine A. High1,2,4,*
  1. 1Department of Pediatrics and Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  2. 2Howard Hughes Medical Institute, Philadelphia, PA 19104, USA.
  3. 3Gene Therapy and Vaccine Program, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  4. 4Department of Pediatrics, Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  1. *Corresponding author. E-mail: high{at}email.chop.edu (K.A.H.); fmingozzi{at}genethon.fr (F.M.)
  • Present address: Genethon, 1 bis, rue de l’Internationale, 91000 Evry, France.

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