Research ArticleAntibiotics

Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

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Science Translational Medicine  03 Jul 2013:
Vol. 5, Issue 192, pp. 192ra85
DOI: 10.1126/scitranslmed.3006055

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  • Mission accomplished

    Kalghatgi et al. (1) discuss mitochondrial dysfunction and oxidative damage in the adverse effects of bactericidal antibiotics. They conclude that "mitigation strategies such as co-administration with an antioxidant could be used. It will be intriguing to explore these possibilities with appropriate clinical trials". The translational medicine community will be happy to know that these goals have already been accomplished...

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    Competing Interests: None declared.

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