Research ArticleAntibiotics

Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

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Science Translational Medicine  03 Jul 2013:
Vol. 5, Issue 192, pp. 192ra85
DOI: 10.1126/scitranslmed.3006055

Article Information

vol. 5 no. 192 192ra85

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 1, 2013
  • Accepted for publication June 3, 2013
  • .

Author Information

  1. Sameer Kalghatgi1,*,
  2. Catherine S. Spina1,2,3,*,
  3. James C. Costello1,
  4. Marc Liesa3,
  5. J. Ruben Morones-Ramirez1,
  6. Shimyn Slomovic1,
  7. Anthony Molina3,4,
  8. Orian S. Shirihai3 and
  9. James J. Collins1,2,3,
  1. 1Howard Hughes Medical Institute, Department of Biomedical Engineering and Center of Synthetic Biology, Boston University, Boston, MA 02215, USA.
  2. 2Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
  3. 3Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
  4. 4Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27105, USA.
  1. Corresponding author. E-mail: jcollins{at}bu.edu
  • * These authors contributed equally to this work.

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