Research ArticleProstate Cancer
A Preclinical Xenograft Model Identifies Castration-Tolerant Cancer-Repopulating Cells in Localized Prostate Tumors
- Roxanne Toivanen1,
- Mark Frydenberg1,2,
- Declan Murphy3,
- John Pedersen1,4,
- Andrew Ryan4,
- David Pook1,
- David M. Berman5,
- Australian Prostate Cancer BioResource1,
- Renea A. Taylor1,6,* and
- Gail P. Risbridger1,*,†
- 1Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia.
- 2Department of Surgery, Monash University, Clayton, Victoria 3800, Australia.
- 3Division of Cancer Surgery, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3800, Australia.
- 4TissuPath Laboratories, Mount Waverley, Victoria 3149, Australia.
- 5Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario K7L 3N6, Canada.
- 6Department of Physiology, Monash University, Clayton, Victoria 3800, Australia.
- ↵†Corresponding author. E-mail: gail.risbridger{at}monash.edu
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Science Translational Medicine 29 May 2013:
Vol. 5, Issue 187, pp. 187ra71
DOI: 10.1126/scitranslmed.3005688
