Research ArticleCancer Immunotherapy

Oncolytic and Immunotherapeutic Vaccinia Induces Antibody-Mediated Complement-Dependent Cancer Cell Lysis in Humans

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Science Translational Medicine  15 May 2013:
Vol. 5, Issue 185, pp. 185ra63
DOI: 10.1126/scitranslmed.3005361

Article Information

vol. 5 no. 185 185ra63

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 19, 2012
  • Accepted for publication April 11, 2013

Author Information

  1. Mi Kyung Kim1,2,*,
  2. Caroline J. Breitbach3,*,
  3. Anne Moon3,
  4. Jeong Heo1,
  5. Yu Kyoung Lee2,
  6. Mong Cho1,
  7. Jun Woo Lee1,
  8. Seong-Geun Kim1,
  9. Dae Hwan Kang1,
  10. John C. Bell3,4,
  11. Byeong Ho Park5,
  12. David H. Kirn3,*, and
  13. Tae-Ho Hwang1,2,*,
  1. 1Pusan National University and Medical Research Institute, Pusan National University, 1-10 Ami-Dong, Seo-Gu, Busan 602-739, South Korea.
  2. 2SillaJen Inc., Jangjeondong Geum Jeong-gu, Busan 609-735, South Korea.
  3. 3Jennerex Inc., 450 Sansome Street, 16th Floor, San Francisco, CA 94111, USA.
  4. 4Centre for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada.
  5. 5Department of Diagnostic Radiology, College of Medicine, Dong-a University, Dongdaesingdong 3-ga Seo-Gu, Busan 602-739, South Korea.
  1. Corresponding authors. E-mail: thhwang{at}pusan.ac.kr (T.-H.H.); davidhkirn{at}gmail.com (D.H.K.)
  • * These authors contributed equally to this work.

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