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Neural Stem Cell–Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies

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Science Translational Medicine  08 May 2013:
Vol. 5, Issue 184, pp. 184ra59
DOI: 10.1126/scitranslmed.3005365

Article Information

vol. 5 no. 184 184ra59

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 19, 2012
  • Accepted for publication April 11, 2013
  • .

Author Information

  1. Karen S. Aboody1,2,*,
  2. Joseph Najbauer1,
  3. Marianne Z. Metz1,
  4. Massimo D’Apuzzo3,
  5. Margarita Gutova1,
  6. Alexander J. Annala1,
  7. Timothy W. Synold4,
  8. Larry A. Couture5,
  9. Suzette Blanchard6,
  10. Rex A. Moats7,
  11. Elizabeth Garcia1,
  12. Soraya Aramburo1,
  13. Valerie V. Valenzuela1,
  14. Richard T. Frank1,
  15. Michael E. Barish1,
  16. Christine E. Brown8,
  17. Seung U. Kim9,
  18. Behnam Badie2 and
  19. Jana Portnow10
  1. 1Department of Neurosciences, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  2. 2Division of Neurosurgery, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  3. 3Department of Pathology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  4. 4Department of Clinical and Molecular Pharmacology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  5. 5Center for Applied Technology Development, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  6. 6Division of Biostatistics, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  7. 7Department of Radiology, Children’s Hospital of Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA.
  8. 8Department of Cancer Immunotherapeutics and Tumor Immunology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  9. 9Division of Neurology, Department of Medicine, UBC Hospital, University of British Columbia, Vancouver, British Columbia V6T2B5, Canada.
  10. 10Department of Medical Oncology and Experimental Therapeutics, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA.
  1. *Corresponding author. E-mail: kaboody{at}coh.org

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