Research ArticleAortic aneurysm

Angiotensin-Converting Enzyme–Induced Activation of Local Angiotensin Signaling Is Required for Ascending Aortic Aneurysms in Fibulin-4–Deficient Mice

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Science Translational Medicine  01 May 2013:
Vol. 5, Issue 183, pp. 183ra58
DOI: 10.1126/scitranslmed.3005025

Article Information

vol. 5 no. 183 183ra58

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 24, 2012
  • Accepted for publication March 18, 2013
  • .

Author Information

  1. Jianbin Huang1,*,
  2. Yoshito Yamashiro1,,
  3. Christina L. Papke1,,
  4. Yuichi Ikeda2,3,,
  5. Yanling Lin1,
  6. Miteshkumar Patel1,
  7. Tadashi Inagami4,
  8. Victoria P. Le5,
  9. Jessica E. Wagenseil5 and
  10. Hiromi Yanagisawa1,
  1. 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390–9148, USA.
  2. 2Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390–9148, USA.
  3. 3Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390–9050, USA.
  4. 4Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, TN 37235, USA.
  5. 5Department of Biomedical Engineering, St. Louis University, St. Louis, MO 63103–2010, USA.
  1. Corresponding author. E-mail: hiromi.yanagisawa{at}utsouthwestern.edu
  • * Deceased.

  • These authors contributed equally to this work.

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