06 March 2013
Vol 5, Issue 175
  • Contents

    • Focus

      • Seeing the Light

        One-time gene therapy resulted in multiyear visual improvement, and new approaches were used to evaluate effects on retinal structure.

    • Commentary

    • Research Articles

    • Editors' Choice

      • Dead or Alive? Nanopatrols Report

        New nanosensor-based imaging platform reports on transplanted cell viability.

      • Energy Hunting(tin)

        Vesicles move down neuronal axons powered by local glycolysis, a process that requires huntingtin, the protein defective in Huntington’s disease.

      • Imaging the Beating Heart

        Intravital microscopy of mouse hearts reveals rapid immune cell influx after a heart attack.

About The Cover

Cover image expansion

ONLINE COVER Expanding Our Reach. A luminous hand, outstretched, strives to cradle the world; in November 2012, leaders in cancer research and policy attempted to do the same. Representatives from 15 economically diverse countries met at the U.S. National Institutes of Health to discuss ways to deal with the global burden of cancer. Of the 12.7 million newly diagnosed cases each year, more than half occur in less-developed regions of the world. In fact, cancers now account for more than 15% of the world’s annual deaths. In this week’s Commentary, Varmus and Kumar outline recommendations from the meeting to address the growing international challenge of cancer. [CREDIT: Y. HAMMOND/SCIENCE TRANSLATIONAL MEDICINE]